… -specific phosphorylation in vivo, mediated by Neuropilin-1. These … -developed computational
models of VEGF distribution and … VEGF production by skeletal muscle; or degradation of …

… bioavailability and interaction with the co-receptor Neuropilin-1. … both in vitro and in vivo
experimental evidence, VEGF xxx a … Computational modelling of systems pharmacology have …

… tyrosine kinases VEGFR-1 and VEGFR-2. We focus here on … This evidence suggests that, in
vitro, VEGF-A121a can bind … cells in vitro suggests that these components are interacting (or …

… -scale model of vascular regulation in skeletal muscle in vivo. Figure … In this thesis, I describe
the first computational model to … Neuropilin-1 promotes VEGFR-2 trafficking through Rab11 …

… receptors called neuropilins (NRP1 and NRP2) that bind VEGF directly … 1999 In vivo
assessment of vascular endothelial growth factor-induced … 2000 The interaction of neuropilin-1 …

… cells and to VEGF receptors VEGFR2 and neuropilin-1. PR1P … In this assay, we adhered
recombinant VEGFR-1, VEGFR-2, … computational models of VEGF transport in skeletal muscle, …

… receptor 2 (VEGFR-2) but cannot bind to the neuropilin receptor… VEGFR-1 and VEGFR-2 are
expressed in endothelial cells … vitro experiments to determine whether Wnt5a leads to VEGF-…

… of VEGFR-1 has higher affinity for VEGF than VEGFR-2, and … in in vivo models, most of what
we know about VEGFR-2 … how VEGFR-2 acts as a mechanoreceptor and closely interacts …

… of VEGFR-2 with Ig domain 5 of VEGFR-1. The full-length D7(… receptor trafficking: Insights
from a computational model. PLOS … reveals in vivo membrane protein interactions. Integr. Biol. …

… primarily in brain, heart and skeletal muscle [14] and in … The ability of RCAN1.4 to regulate
vascular formation in vivo … to VEGFR-1, phospho-VEGFR-2 (Y1175), VEGFR-1, phospho…